With new indications, Embosphere ® listed in the two decades after continue to blaze new trails

Embosphere ® microsphere has won FDA approval, can be used for vascular embolization to control the bleeding of the peripheral vascular system.As the first obtain the approval of the spherical embolization agent, this is another indication of Embosphere many initiative, consolidate its as clinical research and the status of clinical prove most circular embolic agents, with a consistent and predictable results effective embolism.

Embosphere was originally in Paris, France Lariboisiere hospital development, the initial clinical study was conducted in the late 1980 s.Before Embosphere, standard for therapeutic embolization of embolization agent initially only includes the spherical polyvinyl alcohol (PVA) and gelatin sponge particles, but the two products are flawed.

In essence, the size of the non spherical PVA particles are different.This kind of irregular may lead to uncontrolled embolism and micro catheter jam.1, 2,Compared with spherical embolic agents, gelatin sponge is associated with more inflammation, and preparation and is usually very time consuming, and to obtain uniform size particles is also a challenge.2, 3Desire and demand for better embolization agent drives we developed Embosphere microspheres.

Embosphere spherical made from three crosslinking acrylate copolymer proprietary formula, the imitation of the natural contour in the lumen, realize "joint and fill" the effect.In addition, the hydrophilic surface can prevent the catheter lumen and gathered in the vascular system.*

Comparative study shows that Embosphere has many advantages than its predecessors.First of all, it is only used by a particle size has a direct correlation between occluded artery diameter and circular embolization agent.1Other competing goods without this correlation, and has been proved to have higher body deformation rateSo we can not provide predictable embolism results.1, 4Data also showed that compressible Embosphere microspheres as high as 33%, conducive to the promotion of micro catheter through sex.5After the application of these microspheres will return to its diameter, resulting in a sustained and targeted results.

Embosphere, now, more than 20 years in the past, is the most extensive and the most widely clinical application of circular embolization agent, has hundreds of thousands of global operations and more than 220 peer-reviewed clinical proved in this paper.

Embosphere is a kind of performance and quality are very stable microsphere, is still in the continuous innovation for many years.Since 1997, it is the first commercial microspheres agent.Embosphere in 2002, is the first package embolic agents in the syringe, and the first to obtainUterine fibroid embolization(UFE) embolization agent approved by the indications.Fast forward to 2017, Embosphere won the firstProstatic artery embolization(PAE) indication approved in the United States.Today, we recognize the first - the recent indications of embolization in the United States, to control bleeding in the peripheral vascular system.

The number of first reflected the high levels of quality and performance of Embosphere, also reflect the Merit that dominate the continued dedication of embolism and support for the doctor provide minimally invasive treatment.

Embosphere schedule - are available for the first time, the most studied and embolism

reference

  1. Pelage, J., Laurent, A., Wassef, M., et al. (2002). The Uterine artery embolization in the sheep: Comparison of acute effects with polyvinyl alcohol particles and calibrated microspheres, Radiology, Aug.224 (2) : 436-445.
  2. He - Kirsch, r. (2008), Jun). Do particle size and the type of matter?Obtained from (In English)https://evtoday.com/2008/06/EVT0608_04.php?Center = 156
  3. Oh, J., Lee, H., Chun, H., et al. (2015). Evaluation of arterial impairment after experimental gelatin sponge embolization in a rabbit takes model. The Korean J Radiol, Jan - Feb;16 (1) : 133-138.
  4. Verret, v. Ghegediban, s., Wassef, M., et al. (2011). The arterial distribution of Embozene and Embosphere microspheres in The sheep kidney and uterus embolization models. J Vasc Interv Radiol, Feb.22 (2) : 220-228.
  5. Laurent, a. Beaujeux, R., Wassef, M., et al. (1996). Trisacryl gelatin microspheres for therapeutic embolization, I: Development and in vitro evaluation. The AJNR Am J Neuroradiol, Mar.17 (3) : 533-540.

* internal data